Vitamins and supplements are easily one of the biggest categories in ecommerce. There is no question about that. There are thousands of vitamin brands and thousands of supplement brands; lots of players try to breakthrough in the space because it’s known to have a massive total addressable market and generally high customer lifetime value.
According to the CDC (Centers for Disease Control and Prevention), over 57% of all U.S. adults over 20 years old have used a dietary supplement in the last 30 days. That is huge. That is over 75,000,000 potential customers for these vitamin and supplement brands and a big reason why there is a rush to compete. This certainly doesn’t make it easy for the consumer, though. Which vitamin brand should you pick? Which supplements are legit? Which vitamin brands have the best ingredients and best third-party testing regiments?
There are a ton of questions and unfortunately, there are not many sources that give you the honest, objective answers. Every vitamin brand claims they’re the best and have the best manufacturing and production process. Same with every supplement brand.
In our objective, unbiased list below, you can check out some of the most popular vitamin and supplement brands on the market today.
Buoy is an oral rehydration solution that works in just a few drops. This flavorless, hydration solution refills your body with electrolytes and can be mixed into any liquid (even alcohol) Buoy offers 3 variations: hydration, energy, and immunity.
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Jude is the bladder care company that is smashing taboos and making products like pads, liners, and supplements made with pumpkin seed extract and soygerm extract to help strengthen the bladder.
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XWERKS is the maker of unique, science based nutrition products designed to optimize performance and health.
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Ascent Nutrition is a wellness company that formulates and sells high-quality supplements focused on cognitive function, overall vitality, and immune support. Their product line includes unique offerings like algae oil DHA, pine bark extract, and humic & fulvic minerals, all derived from traceable, eco-friendly sources. With a mission to improve health through clean, purposeful nutrition, Ascent Nutrition serves both health-conscious consumers and holistic practitioners.
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Dose crafts expertly formulated organic wellness shots, combining potent, clean ingredients in clinically-researched dosages to support a healthier body daily. Their product line, free from sugar and calories, includes turmeric, aloe vera, elderberry, and milk thistle, boasting enhanced bioavailability and strength. Emphasizing a holistic approach to health, Dose aims to deliver the most effective wellness shots for those seeking natural, functional support for their liver, immunity, skin, and more, backed by a passion for holistic living and natural medicine.
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Four Sigmatic makes crash-free coffee, almost-unbelievable plant protein, and other elevated essentials. Deliciously crafted to work wonders on your day.
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ResBiotic specializes in probiotics aimed at respiratory health, providing innovative supplements that support lung function and overall respiratory well-being. Their products harness the power of beneficial bacteria to help maintain a balanced microbiome.
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One Sol Supps is a women-focused supplement brand offering clean, effective formulas to support fitness, wellness, and hormonal balance. From plant-based protein powders to pre-workouts and metabolism boosters, One Sol products are designed to fuel your body and empower your lifestyle.
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The most effective Energy Formula for gamers. What started as just 3 Tub flavors - Blue Ice, Fruit Punch and Lemon Lime - Quickly evolved into something much more...A movement. A culture. A Community.
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Dr. Berg is a trusted name in health and wellness, known for making complex nutrition science simple and accessible. Specializing in ketogenic and intermittent fasting strategies, Dr. Eric Berg has helped millions take control of their health through educational content, high-quality supplements, and practical guidance. His brand is built on the philosophy that real, sustainable health starts with understanding your body’s needs—focusing on natural ingredients, holistic healing, and evidence-based nutrition. Whether you’re looking to improve energy, support weight loss, or optimize overall wellness, Dr. Berg provides the tools and knowledge to help you thrive.
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Personalized prenatals to optimize your fertility outcomes, delivered right to your door.
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Sports drinks are chock full of added sugar and artificial flavors. Cure says "no thank you". Cure is made with only premium and organic ingredients like coconut water and pink Himalayan salt. They took what existed in nature and mixed it to tasty perfection.
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